Vytorin and INR? Al?

[RickKiem]

I was recently switched from Lipotor to Vytorin by my Cardio and have been fighting my INR ever since. I asked him when he prescribed it if it would have any effect and he said that as far as he knew it shouldn't. This is a combination drug that combines ezetimibe(Zetia) and simvastatin(Zocor). I can find information about Zocor and do not think it is causing my problem. I can not find anything that tells me how I might expect Zetia to effect my INR. Anyone have and information they could share? :confused:

Thanks,
Rick

[Marty]

I was recently switched from Lipotor to Vytorin by my Cardio and have been fighting my INR ever since. I asked him when he prescribed it if it would have any effect and he said that as far as he knew it shouldn't. This is a combination drug that combines ezetimibe(Zetia) and simvastatin(Zocor). I can find information about Zocor and do not think it is causing my problem. I can not find anything that tells me how I might expect Zetia to effect my INR. Anyone have and information they could share? :confused:

Thanks,
Rick

Rick ,I looked up Zetia in the PDR and they specifically stated that it had no effect on warfarin metabolism or prothrombin time. However I have never liked combo drugs. If something goes wrong one is never sure which drug is causing it. Maybe you should take Zetia and Zocor separately, one at at a time ,and check your PT after one week for each drug. Marty

[allodwick]

I've seen a few people taking Vytorin without problems. There could be a little effect from changing statins but it should not be very much.

[RickKiem]

Thanks for you input guys. I can't figure out what is going on... I quess I will just have to find the right dose....again....

Happy holidays!
Rick